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a-dex only for pct
- geneticfreak60
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thanx for any advice
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- Netro
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It is not what car you drive, but the size of the arm hanging out the window.
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- MxT
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No Preservatives. 100% Juice
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- admin
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- MxT
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No Preservatives. 100% Juice
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- Martin77
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The feedback mechanism reacts to two things (very crudly stated), amount of Estrogens present and amount of Testosterone present. When the bodies natural Test dips below normal, only Estrogen will inhibit the HPTA. Block the Estrogen receptor sites with a weak Estrogen like Clomid/Kessar and voila, the Hypothalamus thinks it needs to get the Test going again and starts the whole process via the HPTA. The hCG only helps to get one of the blocks in the loop going quicker and is no substitute for Kessar/Clomid. If the hCG is dosed too high, it will just increase the feedback again and the whole PCT is messed up again ....
I'll however check out your suggestion to see if studies with AI's on fertility have been done.
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- admin
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You are correct that AI's do not affect the HPTA directly, but since estrogen levels drop the body will respond by releasing more LH than normal to counter the drop in estrogen by means of increasing androgens and thus increasing the amount of androgens the aromatase enzyme will aromatize into estrogens. But remember that the aromatase enzyme get inhibited by Letrozole, so it will not aromitize into estrogens, effectively increasing even more LH.
LH will stimulate the testis to produce more testosterone (androgens) and that is how it works as part of your PCT.
Because estrogen is part of the negative feedback loop of the HPTA, Letrozole (and other anti-estrogens) are able to raise testosterone in male subjects. Letrozole was studied in men, and found to significantly increase LH levels to a 339 and 323% in the young and the elderly, respectively and Testosterone by 146 and 99%, respectively. (3) Letrozole was also able to produce a peak LH response to Gonadatropin Releasing Hormone equal to a 152 and 52% increase from baseline in either young or older men, respectively (3). In a similar study 0.02 mg of Letrozole increased testosterone by 45% after 2 days.
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- Martin77
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